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KMID : 0191120220370070058
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Journal of Korean Medical Science
2022 Volume.37 No. 7 p.58 ~ p.58
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Guillain-Barre Syndrome After Two COVID-19 Vaccinations: Two Case Reports With Follow-up Electrodiagnostic Study
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Kim Jun-Woo
Kim Yong-Gyun
Park Yu-Chan
Choi Sae-Mi
Lee Sang-Gon
Min Hye-Joon
Kim Mi-Jung
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Abstract
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Guillain-Barre syndrome (GBS) is an immune-mediated acute polyradiculoneuropathy and commonly occurs after a preceding infection or immunization sequalae. Following the severe acute respiratory syndrome-coronavirus-2 virus pandemic with co-introduction of massive vaccinations, several GBS cases associated with coronavirus disease 2019 (COVID-19) infection per se or after vaccination for COVID-19 were reported internationally. Herein, we report two cases of Korean GBS presenting with tetraplegia after two different COVID-19 vaccinations (42-year old man by AstraZeneca and 48-year woman by Pfizer vaccines) within four weeks after vaccination. The patients were diagnosed with clinical examination, serial electromyography, and compatible laboratory results and improved after comprehensive rehabilitative treatment and intravenous immunoglobulin therapy. Furthermore, we performed an electrodiagnostic follow-up study of each case to examine their unique characteristics.
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KEYWORD
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Guillain-Barre Syndrome (GBS), COVID-19 Vaccination, Electrodiagnosis, Comprehensive Rehabilitation Therapy, Case Report
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